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Posts: 9
Reply with quote  #1 

For those that are suffering from age related hair loss or those that are getting grey faster. The following study might be of an interest:

Evidence for an age-correlated change in glutathione metabolism enzyme activities in human hair follicle.


L'OREAL Research Laboratory, Aulnay sous bois, France.


In this investigation, glutathione peroxidase (GSH-PX), glutathione reductase (GSSG-RD), glutathione-S-transferase (GSH-S-T), gamma-glutamyl transpeptidase (gamma-GT) and glucose-6-phosphate dehydrogenase (G6PDH) were measured in human hair follicle obtained by plucking as source of keratinized cells. This non-invasive method was used on 27 men and women volunteers ranging from 19 to 102 years. Our results show that GSSG-RD, GSH-S-T, gamma-GT and G6PDH activities decrease as a function of age, whereas GSH-PX activity does not vary. We discriminated 2 groups: a first one from 19 to 60 years with a large dispersion of the enzymatic activities and a second one corresponding to elderly people (up to 70) with a smaller dispersion of the values. This study suggests the keratinocytes possess an age-correlated enzymatic detoxification response potential.


Posts: 13
Reply with quote  #2 

Does this imply that taking GLutathione at an advanced age might help with the health texture and color of the hair?


Posts: 8
Reply with quote  #3 
It looks like that is the case as we can see below:

"In male-pattern baldness, androgens (male hormones) target hair follicles, which convert them into even stronger hormones. The unfortunate result is that hair growth slows or stops. M.E. Sawaya at the University of Miami showed that the conversion of these hormones can be influenced by glutathione, suggesting that GSH plays a protective role.

Age-related GSH losses in human hair follicles is part of the total body glutathione depletion described in chapter 6 on aging. Working at the L'Oreal research lab, M. Kermici measured follicular GSH activity in men and women ranging in age from 19 to 102 years and found a significant decline up until about age seventy, then a slower second decline. "

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